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Clinicians may not call themselves biohackers, but a growing number now act like them. While they prescribe evidence-based basics to their patients, many are quietly running sophisticated, personalized experiments on themselves. We surveyed 129 of them to find out what they’re actually doing, and the results reveal a quiet revolution unfolding in the group chats of top medical professionals.
Some are cautious. Some are full-stack experimenters. But most are somewhere in between, layering basics with emerging options, testing and adjusting as they go. From our data, a clear picture emerged. We found that these clinicians don’t fall on a simple spectrum; they cluster into four distinct tribes:

The Minimalists (18%): They stick to a few high-conviction basics.
The Builders (45%): They have a core regimen of evidence-based supplements and lifestyle habits.
The Pioneers (26%): They methodically experiment with off-label drugs and more advanced diagnostics.
The Full-Stack Biohackers (11%): They run comprehensive, multi-modal optimization protocols with aggressive testing and often injectable medications.
The question isn’t whether health optimization is happening amongst clinicians. It’s what shape it’s taking, and how far the envelope is getting pushed. Throughout this piece, we’ll explore not just what these clinicians are doing, but how their behaviors differ across these groups—offering a blueprint for where preventative health is heading.